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Losartan is a drug with generic name of Lozartan Potassium-Hydrochlorothiazide. Losartan is a combine diuretic such as hydrochlorothiazide and an angiotensin II receptor (type AT 1) antagonist. Angiotensin II is a powerful vasoconstrictor. Losartan works by blocking the binding of angiotensin II to the AT 1 receptor in the many tissues in our body.
Losartan is prescribed to treat hypertension or high blood pressure. Losartan may be prescribed for purposes not mentioned here.
Losartan belongs to the FDA pregnancy category C (for first trimester) and FDA pregnancy category D (for second and third trimester). Losartan should not be administered for pregnant women. Drugs that act directly on the renin-angiotensin system, such as Losartan, can cause fetal and neonatal morbidity. Stop taking Losartan if you are pregnant or could become pregnant during the treatment period.
It is not known whether Losartan passes to breast milk of nursing mothers but studies shows that Losartan were shown to be present in rat milk. Always ask for your doctor's prescriptions before taking Losartan if you are breast-feeding a baby.
Losartan should be prescribed with caution in infants. Safety and effectiveness of Losartan in infants have not been studied yet. Losartan may cause Hypotension, Oliguria, and Hyperkalemia. Losartan crosses the placenta. Risks such as Fetal or neonatal jaundice and Thrombocytopenia may occur with the use of Losartan. Always ask for your doctor's prescription before taking Losartan drug.
There are no overall differences in effectiveness or safety between older and younger patients but still greater sensitivity of some older individuals cannot be ruled out.
Take Losartan as directed by your doctor. You may ask your doctor, nurse, or pharmacist for things that you do not understand. Losartan comes as a tablet that is usually taken once or twice a day. Take Losartan every morning if you are taking Losartan once a day and take Losartan every morning and afternoon if you are taking Losartan twice a day. Take Losartan with meals. Always follow your doctor's prescription in taking Losartan.
Losartan controls high blood pressure. Do not stop taking Losartan even if you feel well. Talk to you doctor first before you stop taking Losartan drug.
Obtain the exact dosage of Losartan from your doctor or physician. The dosage of Losartan may vary from person to person.
The usual dosage of Losartan is one tablet a day. Losartan dosage may also be increased to two tablets a day if the patient does not respond effectively on the usual dosage of Losartan. The maximum dosage of Losartan drug must be two tablets a day only.
Losartan may be taken with or without food. Losartan may also be administered together with other antihypersensitive agents. There is no necessary dosage adjustment of Losartan for the elderly patients.
Overdose of Losartan includes the following:
Take the missed dose of Losartan drug as soon as you remember but if it is almost time for the next Losartan dose, skip the missed one and take the subsequent dose according to schedule. It is important to remember not to take a double dose of Losartan medication.
Side effects of Losartan drug are not common and are unlikely to occur. However, tell your doctor immediately if you experience any of the following side effects.
- Allergic reaction such as swelling of the face, eyes, lips, tongue, arms, or legs;
- Difficulty breathing;
- Difficulty swallowing;
- Soar throat with fever;
- Unusual bleeding or bruising;
Consult your doctor if the following conditions do not go away:
- Hair loss;
- Muscle aches;
- Stomach pain;
Other side effects not mentioned here may also occur. Inform your doctor as soon as possible if you feel anything unusual or bothersome.
Have caution in taking different other medications while taking Losartan. Tell your doctor or pharmacist immediately if you are taking Losartan together with any of the following:
- Anti-inflammatory medications such as ibuprofen (motrin, nuprin, or advil) and naproxen (aleve);
- Barbiturates such as phenobarbital;
- Corticosteroids such as prednisone;
- Digoxin such as lanoxin and lanoxicaps;
- Diuretics (water pill);
- Lithium such as eskalith and lithobid;
- Medications fro diabetes;
- Other medications for high blood pressure;
- Potassium supplements;
- Probenecid (benemid);
Take the following at least 1 hour after taking Losartan:
- Cholestyramine such as questran and prevalite;
- Colestipol such as colestid;
Other medications not mentioned above may also interfere with the function of Losartan. Talk to your doctor first before buying any drugs or over-the-counter medicines.
Other Brand Names
In some countries Losartan may also be known as: