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Hyzaar is a drug with generic name of Lozartan Potassium-Hydrochlorothiazide. Hyzaar is a combine diuretic such as hydrochlorothiazide and an angiotensin II receptor (type AT 1) antagonist. Angiotensin II is a powerful vasoconstrictor. Hyzaar works by blocking the binding of angiotensin II to the AT 1 receptor in the many tissues in our body.
Hyzaar is indicated to treat hypertension or high blood pressure. Hyzaar may be indicated for purposes not mentioned here.
Hyzaar belongs to the FDA pregnancy category C (for first trimester) and FDA pregnancy category D (for second and third trimester). Hyzaar should not be administered for pregnant women. Drugs that act directly on the renin-angiotensin system, such as Hyzaar, can cause fetal and neonatal morbidity. Stop taking Hyzaar if you are pregnant or could become pregnant during the treatment period.
It is not known whether Hyzaar passes to breast milk of nursing mothers but studies shows that Hyzaar were shown to be present in rat milk. Always ask for your doctor's prescriptions before taking Hyzaar if you are breast-feeding a baby.
Hyzaar should be indicated with caution in infants. Safety and effectiveness of Hyzaar in infants have not been studied yet. Hyzaar may cause Hypotension, Oliguria, and Hyperkalemia. Hyzaar crosses the placenta. Risks such as Fetal or neonatal jaundice and Thrombocytopenia may occur with the use of Hyzaar. Always ask for your doctor's prescription before taking Hyzaar drug.
There are no overall differences in effectiveness or safety between older and younger patients but still greater sensitivity of some older individuals cannot be ruled out.
Take Hyzaar as directed by your doctor. You may ask your doctor, nurse, or pharmacist for things that you do not understand. Hyzaar comes as a tablet that is usually taken once or twice a day. Take Hyzaar every morning if you are taking Hyzaar once a day and take Hyzaar every morning and afternoon if you are taking Hyzaar twice a day. Take Hyzaar with meals. Always follow your doctor's prescription in taking Hyzaar.
Hyzaar controls high blood pressure. Do not stop taking Hyzaar even if you feel well. Talk to you doctor first before you stop taking Hyzaar drug.
Obtain the exact dosage of Hyzaar from your doctor or physician. The dosage of Hyzaar may vary from person to person.
The usual dosage of Hyzaar is one tablet a day. Hyzaar dosage may also be increased to two tablets a day if the patient does not respond effectively on the usual dosage of Hyzaar. The maximum dosage of Hyzaar drug must be two tablets a day only.
Hyzaar may be taken with or without food. Hyzaar may also be administered together with other antihypersensitive agents. There is no necessary dosage adjustment of Hyzaar for the elderly patients.
Overdose of Hyzaar includes the following:
Take the missed dose of Hyzaar drug as soon as you remember but if it is almost time for the next Hyzaar dose, skip the missed one and take the subsequent dose according to schedule. It is important to remember not to take a double dose of Hyzaar medication.
Side effects of Hyzaar drug are not common and are unlikely to occur. However, tell your doctor immediately if you experience any of the following side effects.
- Allergic reaction such as swelling of the face, eyes, lips, tongue, arms, or legs;
- Difficulty breathing;
- Difficulty swallowing;
- Soar throat with fever;
- Unusual bleeding or bruising;
Consult your doctor if the following conditions do not go away:
- Hair loss;
- Muscle aches;
- Stomach pain;
Other side effects not mentioned here may also occur. Inform your doctor as soon as possible if you feel anything unusual or bothersome.
Have caution in taking different other medications while taking Hyzaar. Tell your doctor or pharmacist immediately if you are taking Hyzaar together with any of the following:
- Anti-inflammatory medications such as ibuprofen (motrin, nuprin, or advil) and naproxen (aleve);
- Barbiturates such as phenobarbital;
- Corticosteroids such as prednisone;
- Digoxin such as lanoxin and lanoxicaps;
- Diuretics (water pill);
- Lithium such as eskalith and lithobid;
- Medications fro diabetes;
- Other medications for high blood pressure;
- Potassium supplements;
- Probenecid (benemid);
Take the following at least 1 hour after taking Hyzaar:
- Cholestyramine such as questran and prevalite;
- Colestipol such as colestid;
Other medications not mentioned above may also interfere with the function of Hyzaar. Talk to your doctor first before buying any drugs or over-the-counter medicines.
Other Brand Names
In some countries Hyzaar may also be known as: