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Aponal. |
Without a Prescription
Aponal is a tricyclic antidepressant.
Aponal is prescribed only for a short time (no more than 8 days).
Aponal is prescribed to patients in order to ease their symptoms of anxiety and / or depression.
Aponal is prescribed to relieve troublesome itching from certain skin conditions (atopic dermatitis, eczema, neurodermatitis).
Aponal is not known how this medication decreases itching.
Aponal may work by blocking a certain natural substance (histamine) that your body makes during an allergic reaction.
Some medication is absorbed into the body when the cream is applied.
The decrease in itching may be a result of drowsiness or some other effect in the brain that causes you not to notice or be bothered by the itching.
Warnings
Some medical disorders are known to harmfully interact with a treatment with Aponal. These include:
- Bipolar Disorder (manic-depressive disorders);
- Diabetes (a treatment with Doxepin could lower or raise your blood sugar levels);
Side Effects
Aponal side effects that you should report to your health care professional or doctor as soon as possible:
- Agitation;
- Blurred vision;
- Burning/stinging at the application site;
- Changes in taste;
- Confusion;
- Dark urine;
- Decreased sexual ability/interest;
- Depression;
- Dizziness;
- Drowsiness;
- Dry mouth;
- Easy bruising/bleeding;
- Fainting;
- Fast/irregular heartbeat;
- Fever;
- Itching/swelling (especially of the face/tongue/throat);
- Loss of coordination;
- Mental/mood changes;
- Muscle weakness/spasms;
- Numbness/tingling of the hands/feet;
- Pain/redness/swelling of arms or legs;
- Persistent heartburn;
- Persistent nausea/vomiting;
- Persistent sore throat;
- Rash;
- Restlessness;
- Ringing in the ears;
- Seizures;
- Severe constipation;
- Severe dizziness;
- Severe stomach/abdominal pain;
- Signs of infection;
- Slurred speech;
- Swelling of the hands/feet;
- Trouble breathing;
- Trouble urinating;
- Vision changes;
- Weakness on one side of the body;
- Weight gain;
- Yellowing eyes/skin;
Overdose
The average symptoms that could be triggered by an overdose with Aponal include:
- Agitation;
- Big/wide pupils;
- Blurred vision;
- Coma;
- Confusion;
- Extreme drowsiness;
- Fainting;
- Fainting;
- Fast/irregular heartbeat;
- Feeling cold or hot;
- Feeling light-headed;
- Hallucinations;
- Hallucinations;
- Loss of consciousness;
- Muscle stiffness;
- Seizure (convulsions);
- Seizures;
- Severe dizziness;
- Uneven heartbeats;
- Vomiting;
Contraindications
Aponal is contraindicated if you have any of the following conditions:
- if you are allergic to other tricyclic antidepressants (amitriptyline);
- if you are allergic to Aponal;
- if you have any other allergies;
- if you have breathing problems (bronchitis, emphysema);
- if you have certain eye problem (narrow-angle glaucoma);
- if you have certain eye problem (open-angle glaucoma);
- if you have certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG);
- if you have conditions that may increase your risk of seizures (other brain disease, alcohol withdrawal);
- if you have diabetes, eating disorders (bulimia);
- if you have family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death);
- if you have heart problems (irregular heartbeat);
- if you have kidney problems;
- if you have liver problems;
- if you have long-term constipation;
- if you have long-term heartburn;
- if you have overactive thyroid (hyperthyroidism);
- if you have personal or family history of mental/mood conditions (bipolar disorder, psychosis, suicide);
- if you have problems urinating (due to enlarged prostate);
- if you have seizures;
Interactions
Do not take Aponal with any of the following drugs:
- Albuterol;
- Alcohol;
- Amiodarone;
- Amitriptyline;
- Amphetamine;
- Amprenavir/fosamprenavir;
- Anticholinergics;
- Antidepressants;
- Arbutamine;
- Atropine;
- Barbiturates;
- Belladonna alkaloids;
- Carbamazepine/phenytoin;
- Certain anti-seizure drugs;
- Certain drugs for heart rhythm such as flecainide/propafenone;
- Certain drugs for high blood pressure;
- Certain HIV protease inhibitors;
- Chlorpropamide;
- Cimetidine;
- Cisapride;
- Clonidine;
- Digoxin;
- Disopyramide;
- Dofetilide;
- Drugs affecting liver enzymes that remove doxepin from your body;
- Drugs for Parkinson's disease such as benztropine;
- Duloxetine;
- Epinephrine;
- Fluvoxamine;
- Furazolidone;
- Guanadrel;
- Guanethidine;
- Halofantrine;
- Haloperidol;
- Inhaled bronchodilators;
- Isocarboxazid;
- Levodopa;
- Linezolid;
- Lithium;
- Macrolide antibiotics (erythromycin);
- MAO inhibitors;
- Methylphenidate;
- Moclobemide;
- Nasal decongestants;
- Paroxetine;
- Phenelzine;
- Phenobarbital;
- Phenothiazines;
- Phenylephrine;
- Pimozide;
- Procainamide;
- Procarbazine;
- Quinidine;
- Rasagiline;
- Reserpine;
- Salmeterol;
- Scopolamine;
- Selegiline;
- Sertraline;
- Sibutramine;
- Sotalol;
- Sparfloxacin;
- St John's wort;
- Stimulants;
- Sulfonylurea anti-diabetic medication;
- Terbinafine;
- Thioridazine;
- Thyroid medication;
- Tolazamide;
- Tranylcypromine;
- Trazodone;
- Valproic acid;
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